Buy Starch, 2-hydroxypropyl ether | 9049-76-7
Buy Starch, 2-hydroxypropyl ether | -76-7
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Biochemical Properties
Starch, 2-hydroxypropyl ether, plays a significant role in biochemical reactions due to its modified structure. The hydroxypropyl groups introduced into the starch molecule enhance its interaction with various enzymes, proteins, and other biomolecules. For instance, it interacts with amylase enzymes, which catalyze the hydrolysis of starch into simpler sugars. The presence of hydroxypropyl groups can affect the binding affinity and catalytic efficiency of amylase, leading to altered reaction kinetics . Additionally, this compound, can interact with proteins through hydrogen bonding and hydrophobic interactions, influencing protein stability and functionality.
Cellular Effects
This compound, has been shown to influence various cellular processes. In different cell types, it can affect cell signaling pathways, gene expression, and cellular metabolism. For example, in fibroblast cells, this compound, can modulate the expression of genes involved in extracellular matrix production, leading to changes in cell adhesion and migration. Additionally, it can impact cellular metabolism by altering the uptake and utilization of glucose, thereby influencing energy production and storage .
Molecular Mechanism
The molecular mechanism of action of this compound, involves its interaction with biomolecules at the molecular level. The hydroxypropyl groups can form hydrogen bonds with amino acid residues in enzymes, leading to changes in enzyme conformation and activity. This can result in either inhibition or activation of enzymatic reactions. Furthermore, this compound, can influence gene expression by interacting with transcription factors and other regulatory proteins, thereby modulating the transcriptional activity of specific genes .
Temporal Effects in Laboratory Settings
In laboratory settings, the effects of this compound, can change over time. The stability and degradation of the compound are critical factors that influence its long-term effects on cellular function. Studies have shown that this compound, remains stable under physiological conditions for extended periods, allowing for sustained interactions with biomolecules. Over time, it may undergo partial degradation, leading to the release of hydroxypropyl groups and native starch fragments, which can have different biochemical effects .
Dosage Effects in Animal Models
The effects of this compound, vary with different dosages in animal models. At low doses, it can enhance metabolic processes and improve nutrient absorption. At high doses, it may exhibit toxic or adverse effects, such as gastrointestinal disturbances and metabolic imbalances. Threshold effects have been observed, where a specific dosage range elicits optimal benefits without causing toxicity .
Metabolic Pathways
This compound, is involved in various metabolic pathways. It interacts with enzymes such as amylases and glucosidases, which catalyze the breakdown of starch into glucose and other metabolites. The hydroxypropyl groups can influence the activity of these enzymes, leading to changes in metabolic flux and metabolite levels. Additionally, this compound, can affect the synthesis and degradation of glycogen, a key storage form of glucose in cells .
Transport and Distribution
Within cells and tissues, this compound, is transported and distributed through various mechanisms. It can interact with transporters and binding proteins, facilitating its uptake and localization within specific cellular compartments. The hydroxypropyl groups can enhance the solubility and stability of the compound, allowing for efficient transport and distribution. Additionally, this compound, can accumulate in certain tissues, influencing its overall bioavailability and activity .
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Subcellular Localization
The subcellular localization of this compound, is influenced by its chemical structure and interactions with cellular components. It can be targeted to specific compartments or organelles through post-translational modifications and targeting signals. For example, it may localize to the endoplasmic reticulum or Golgi apparatus, where it can participate in glycosylation reactions and other biochemical processes. The hydroxypropyl groups can also affect its activity and function within these subcellular compartments .
News - What is Starch Ether?
What is Starch Ether?
Starch ether is a modified form of starch, a carbohydrate derived from plants. The modification involves chemical processes that alter the structure of starch, resulting in a product with improved or modified properties. Starch ethers find widespread use in various industrial applications due to their unique characteristics. Some common types of starch ethers include hydroxyethyl starch (HES), hydroxypropyl starch (HPS), and carboxymethyl starch (CMS). Here are key aspects of starch ethers:
1. Chemical Modification:
- Hydroxyethyl Starch (HES): In HES, hydroxyethyl groups are introduced to the starch molecule. This modification enhances its water solubility and makes it suitable for use in pharmaceuticals, as a plasma volume expander, and in other applications.
- Hydroxypropyl Starch (HPS): HPS is produced by introducing hydroxypropyl groups to the starch structure. This modification improves properties such as water solubility and film-forming ability, making it useful in industries like food, textiles, and construction.
- Carboxymethyl Starch (CMS): CMS is created by introducing carboxymethyl groups to starch molecules. This modification imparts properties such as improved water retention, thickening, and stability, making it valuable in applications like adhesives, textiles, and pharmaceuticals.
2. Water Solubility:
- Starch ethers generally exhibit improved water solubility compared to native starch. This enhanced solubility is advantageous in formulations where rapid dissolution or dispersion in water is required.
3. Viscosity and Thickening Properties:
- Starch ethers serve as effective thickeners in various formulations. They contribute to increased viscosity, which is valuable in applications such as adhesives, coatings, and food products.
4. Film-Forming Ability:
- Some starch ethers, especially hydroxypropyl starch, exhibit film-forming properties. This makes them suitable for applications where the creation of a thin, flexible film is desired, such as in the food and pharmaceutical industries.
5. Stabilizing and Binding Properties:
- Starch ethers are often used as stabilizers and binders in a variety of formulations. They help improve the stability of emulsions and contribute to the cohesiveness of products like pharmaceutical tablets.
6. Adhesive Applications:
- Starch ethers find use in adhesives, both in the food industry (e.g., in gum arabic substitutes) and non-food applications (e.g., in paper and packaging adhesives).
7. Textile Sizing:
- In the textile industry, starch ethers are used in sizing formulations to improve the strength and smoothness of yarns during weaving.
8. Pharmaceutical Applications:
- Certain starch ethers are employed in pharmaceutical formulations. For example, hydroxyethyl starch is used as a plasma volume expander.
9. Construction and Building Materials:
- Starch ethers, particularly hydroxypropyl starch and carboxymethyl starch, are used in the construction industry, especially in dry mix mortar formulations. They contribute to improved adhesion, workability, and water retention.
10. Food Industry:
In the food industry, starch ethers are used as thickeners, stabilizers, and emulsifiers in various products, including sauces, dressings, and desserts.
11. Biodegradability:
Starch, being a natural polymer, is generally biodegradable. The biodegradability of starch ethers can vary based on the specific modification and processing methods.
12. Environmental Considerations:
Starch ethers derived from renewable sources contribute to the sustainability of certain applications. They are often chosen for their biocompatibility and eco-friendly characteristics.
Its important to note that the specific properties and applications of starch ethers can vary based on the type of modification and the intended use. Manufacturers provide detailed technical specifications for each type of starch ether to guide formulators in choosing the most suitable variant for their specific applications.
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Post time: Jan-27-
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